In a recent work, we reported that chronic cholesterol depletion using statins leads to significant polymerization , we analyzed the lateral dynamics of the serotonin1A receptor in cholesterol-depleted cells (using statins Notably, our results show that statin-induced dynamic confinement could be reversed by destabilization

Cholesterol and Actin in Neurotransmitter GPCR Signaling: Insights from Chronic Cholesterol Depletion Using Statin

GPCR Activation and Signaling Statins inhibit protein kinase D (PKD) activation in intestinal cells and

immunohistochemistry of paired tissue microarrays containing 1125 cores, representing 43 tumor types, each stained A 12-point immunoreactive scoring (IRS) range was used for interpretation of the staining results.

HE staining, ELISA, and immunohistochemistry were used to evaluate pathological changes and the degree In vitro, qRT‒PCR, immunofluorescence staining, and western blotting were used to determine the dynamic

This finding was further validated by transmission electron microscopy and liperfluo staining to assess