NKTCL), a representative disease model to study EBV-induced lymphomagenesis, incorporating genomic, transcriptomic Single-cell transcriptome further delineated the tumor microenvironment as immune-inflamed, -deficient EBV interacted with transcriptional factors to provoke GPCR interactome (GPCRome) reprogramming. Wei-Li Zhao Tags CCR1 , Epstein-Barr virus , Lymphoma , Microenvironment , Multi-omics , Single-cell transcriptome

< GPCR News < GPCRs in Oncology and Immunology Transcriptomic analysis of human cytomegalovirus to survey Objective: In the present study, the RNA-Seq whole transcriptome of renal transplant (RT) patients was Tags Human cytomegalovirus , Indirect effects , RNA-Seq , Renal transplantation , Transcriptome .

Abstract "We explored the dysregulation of G-protein-coupled receptor (GPCR) ligand systems in cancer transcriptomics regulated together with their upstream partners across cancer subtypes and are associated to specific transcriptional communication , drug repurposing , personalized medicine , signaling network , survival analysis , transcriptomics

< GPCR News < GPCRs in Oncology and Immunology Unbiased multitissue transcriptomic analysis reveals complex between the sympathetic-adrenal medullary axis and the HPA axis was explored by histology and multitissue transcriptomics The transcriptome analysis results showed that the downregulated differentially expressed genes (DEGs Neuroendocrine immunomodulatory axis , Neuroinflammation , SCI-induced immunodeficiency syndrome , Transcriptome

In this study, we aimed to integrate the genetic alterations, protein expression profiles, transcriptomes clustering using both RNA sequencing and proteomics revealed many similarities between the proteome and the transcriptome

Furthermore, Transcriptome sequencing was performed to show enrichment genes and pathways. Transcriptomic sequencing suggested the involvement of the Hippo signaling pathway in the action of RGS20

GPCRs in Oncology and Immunology Comparative Analysis of the GNAI Family Genes in Glioblastoma through Transcriptomics conducted to explore the role of GNAI3 in co-expressed genes and associated signaling pathways using a transcript

system Model Organism Phylogenetics and Evolution Aging Basic and Clinical Pharmacology Proteomic and Transcriptomics

Using a transcriptomic analysis of over 37,000 nuclei, we identified twelve distinct clusters of cells

Thus, based on transcriptomic, proteomic, and phosphoproteomic differential expression data of GPR56

Transcriptomic analysis of Ltb4r2-/- and WT macrophages suggested a role for BLT2 in macrophage migration

Through comprehensive transcriptomic analysis of IM-sensitive and IM-resistant CML groups, we identified

Our earlier transcriptomic analysis identified Urothelial Carcinoma Associated-1 (UCA1) as an LPA-stimulated

Bone marrow (BM) samples were collected at baseline for genomic and transcriptomic analysis (n = 32).

My expertise includes biochemical approaches, proteomics and transcriptomics to name a few.

10:00 AM Student Flash Presentations Health and Disease, Metabolism, Nervous System, Proteomics and Transcriptomics Protein-Coupled Receptors Hailey Steichen Identification of Differentially Expressed Gpr116 (Adgrf5) Transcript

Full Agenda Student Flash Presentations Health and Disease, Metabolism, Nervous System, Proteomics and Transcriptomics Recently, it was shown that transcripts of the postsynaptic aGPCR Latrophilin-3 (Lphn3/Adgrl3) undergo These results demonstrate that identifying precise, tissue-specific transcript variants is critical to These data demonstrate that Adgrf5 transcript variants are cell-specific in the kidney. I am researching the physiological relevance of Adgrf5 (Gpr116) transcript variants in specific cell

transduction Published date September 1, 2023 Abstract "CCN1 and CCN2 are matricellular proteins that are transcriptionally for LPA/S1P-induced CCN1/2 typically involve activation of the small GTP-binding protein Rho and the transcription

< GPCR News < GPCRs in Oncology and Immunology G protein coupled receptor transcripts in human immune this, we developed and validated a sensitive, specific, semi-quantitative method for detecting these transcripts We have used the method to profile GPCR transcripts in white blood cells (WBCs)-B, CD4, CD8, NK, and

< GPCR News < GPCRs in Oncology and Immunology Single cell G-protein coupled receptor profiling of Transcription Here, we set out to establish a transcriptional profile that identifies activated kidney fibroblasts Key results: Transcription factor 21 (Tcf21)+ cells that expressed 2 or 3 of Postn, Acta2 and Pdgfra

quantified with virions harboring β-lactamase fused to the viral protein vpr, early and late HIV-1 transcriptions The amount of HIV reverse transcripts was similar in cells expressing or not EBI2.

reconciling these seemingly opposing roles is still unclear and might be attributed to more than one transcript at isoform resolution, the current strategy identified isoform switching in RHBDF2 via differential transcript

overexpression plasmid was constructed for transfection. qRT‒PCR was used to assess proinflammatory factors transcription In addition, RGS6 overexpression decreased ROS production as well as proinflammatory factor transcription

Mechanistic studies have shown that GPR37 modulates lipid metabolism in tumor cells by promoting SCD1 transcription

type 2 conventional (c)DCs, despite the downregulation of Xcr1, Clec9a, H2-Ab1, Sirpa, and Clec10a transcripts

promoted glioblastoma cell proliferation and survival by activating the kinases AKT and CHK1 and the transcriptional

phosphatase (ALP) staining and alizarin red S staining and detecting the changes of ALP and runt-related transcription

In the hedgehog pathway, bifunctional GLI transcription factors generate both GLI-activators (GLI-A)