CCR12a1, CCR12a2, and CCR12b) in largemouth bass (Micropterus salmoides) The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells Methods & Updates in GPCR Research Generation

August 2022 "Epithelial tube formation requires Rho1-dependent actomyosin contractility to generate the regulates distinct myosin pools and actin cytoskeleton in a ligand-dependent manner during epithelial tube formation

September 2022 "Epithelial tube formation requires Rho1-dependent actomyosin contractility to generate regulates distinct myosin pools and actin cytoskeleton in a ligand-dependent manner during epithelial tube formation

< GPCR News < GPCRs in Oncology and Immunology The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells Published date October 29, 2024 Abstract "The intestinal activated by the gut bacterial metabolite pyruvate, is specifically expressed on type 1 conventional dendritic toward pyruvate on the luminal side, forming transepithelial dendrites (TED). efficient uptake of gut luminal antigens, such as dietary compounds and bacterial particles through TED formation

< GPCR News < GPCRs in Oncology and Immunology CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes Published date March 21, 2023 Abstract "Dendritic cells (DCs) and monocytes

neutrophils (CD11b + Gr1+), monocytes (CD11b + Gr1-Ly6C+ and CD11b + Gr1-Ly6C-), macrophages (F4/80+), and dendritic Gpr141 -/- mice showed increased CD11b + Gr1+ neutrophils, CD11b + Gr1- monocytes, CD11c+ dendritic cells Moreover, CD11c+ dendritic cells (DCs) purified from Gpr141 -/- mice increased cytokine production of functions as a negative regulator of immune responses by controlling the functions of monocytes and dendritic Akira Nakamura, Ryo Goitsuka, Tomonori Kaifu Tags G protein–coupled receptor 141 , autoimmune disease , dendritic