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Here we used zebrafish and mouse models to probe the role of BLT2 in macrophage function during inflammation Using a zebrafish model of tailfin injury, we demonstrated that antisense morpholino-mediated knockdown We further replicated these findings in zebrafish models of islet injury and liver inflammation. Moreover, we established the applicability of our zebrafish findings to mammals by showing that macrophages G Mirmira Tags G-protein coupled receptor (GPCR) , Macrophage , inflammation , metabolism , mouse , zebrafish

Method: OGM was identified in a non-biased zebrafish embryonic development screen and validated with Importantly, OGM was not-acutely toxic to zebrafish and its inhibitory effects were found to spare non-malignant

plan to decipher the roles of N-glycosylation of ADGRG6 in organogenesis and tissue development using zebrafish